Study Summary: GLP-1s and Eating Disorder Risk
This week's focus is an important study by Bartel et al. (2024), exploring how GLP-1s, like semaglutide, might impact individuals with eating disorders.
The authors discuss concerns that GLP-1s may unintentionally worsen or even trigger ED behaviours. They point out that increased feelings of fullness and common side effects like nausea or stomach upset could lead to increased dietary restriction, potentially exacerbating ED symptoms. Furthermore, the study raises a critical point about how GLP-1s might complicate standard ED treatment protocols, which generally involve regular meal patterns.
Interestingly, current research into using GLP-1s specifically for binge eating disorder is mixed, often limited by methodological issues. Consequently, there's not yet strong evidence supporting the use of GLP-1s for treating binge eating or other ED symptoms.
The authors suggest several research avenues, advocating for longer-term studies to identify delayed ED symptoms, better measures distinguishing harmful dietary restriction from healthy restraint, and exploration into personalised treatment approaches.
For clinicians, the article provides practical guidance for discussing GLP-1s with patients, emphasising informed decisions, understanding potential risks, and addressing how these medications might interact with ED treatment.
In summary, while GLP-1s offer substantial benefits in managing diabetes and supporting weight loss, dietitians should carefully consider the potential impacts on eating behaviours, particularly among clients who might be vulnerable to EDs.
Read the full study 👇
https://onlinelibrary.wiley.com/doi/10.1002/eat.24109
Reference
Bartel S, McElroy SL, Levangie D, Keshen A. Use of glucagon-like peptide-1 receptor agonists in eating disorder populations. Int J Eat Disord. 2024 Feb;57(2):286-293. doi: 10.1002/eat.24109. Epub 2023 Dec 22. PMID: 38135891.
Thanks for reading!
Leif
Got feedback? Email leif@glp1dietitianhub.com, I'd love to hear from you.
Note: This newsletter is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional for personalised guidance.
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