Supplementation Considerations for Patients on GLP-1s
There is still limited research on best practice supplementation for patients using these medications. Until clearer guidelines emerge, dietitians must take a patient centred approach, using clinical best judgment to ensure nutritional adequacy. Objective testing, such as blood tests and body composition scans (Dexa), can provide valuable insights into a patient’s nutritional status and guide supplement recommendations.
Common deficiencies associated with rapid weight loss
Protein
Vitamin D
B12
Iron
Calcium
Products that can help fill nutritional gaps
Protein Shakes: Useful for patients struggling to meet protein needs due to reduced appetite.
Nutritionally Complete Meal Replacements: Best used short-term or as a structured part of a meal plan, not a long-term solution.
Multivitamins: Should not replace a food-first approach but can be useful when deficiencies are likely.
Other Commonly Marketed Supplements
These products are widely available, but their necessity and effectiveness vary by individual needs:
Hydration Products
Electrolyte-enhanced drinks can support hydration, particularly for patients experiencing nausea or low fluid intake.
Fibre Supplements
Can be helpful for managing constipation, a common side effect of GLP-1 medications.
Probiotics
May help support gut microbiome balance, especially in patients with digestive discomfort.
Hair, Skin, and Nail Supplements
Often contain biotin, collagen, zinc, and antioxidants, but their role in GLP-1 patients is unclear.
Final Considerations
A food first approach remains best practice, but where intake is insufficient, targeted supplementation can play a valuable role in optimising health and preventing deficiencies. As more evidence emerges, recommendations may evolve. Until then, dietitians should continue to use clinical judgment and a person centred approach.
Thanks for reading!
Leif
Got feedback? Email leif@glp1dietitianhub.com, I'd love to hear from you.
Note: This newsletter is for educational purposes only and should not be considered medical advice. Always consult a qualified healthcare professional for personalised guidance.
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